B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells...
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Assistant Professor of Immunology and Infectious Diseases
Our body is colonized by a robust and diverse ecosystem - the commensal microbiome. When mucosal pathogens infect us, they first encounter our commensals... Read more about Smita Gopinath
We seek to develop and apply technologies (particularly revolving around high-dimensional tissue imaging) to address questions related to host-disease...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
Over the last decade, critical discoveries in immunology and cancer biology have revealed how tumors are shaped by the immune system and how they evolve...
Our group studies how cell migration organizes the communication between the innate and the adaptive immune systems. Specifically, we are interested in...
Center for Immunology and Inflammatory Diseases
Pulmonary and Critical Care Unit
Massachusetts General Hospital
Harvard Medical School
149 13th Street, Room 6-221
Charlestown, MA 02129
Program Head, Graduate Program in Immunology Professor of Medicine he/him/his
Sialic acid O-acetylation, Siglecs and the regulation of hematopoiesis and immunity We are particularly interested in a novel set of pathways in which...
Associate Professor of Medicine, Harvard Medical School
Research focus of my lab is to use novel synthetic biology approaches to manipulate conventional and memory-like Natural Killer (NK) cells to enhance...
The Sen laboratory investigates the regulation of T cell dysfunction and explores epigenetic approaches for T cell engineering. We have found that the...