My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Our laboratory is a core laboratory in the MGH Brain Tumor Immunology and Immunotherapy Program. We are focused on understanding the immune response to...
Over the last decade, critical discoveries in immunology and cancer biology have revealed how tumors are shaped by the immune system and how they evolve...
The Sen laboratory investigates the regulation of T cell dysfunction and explores epigenetic approaches for T cell engineering. We have found that the...
Assistant Professor of Medicine; Director of Translational Science, Immune Effector Cell Therapies
Rapid advances in gene engineering make the previously unimaginable rapidly accessible. The Smith Lab for Genetic and Cellular Engineering uses synthetic...