The primary interest of this laboratory is in the control by genes of the major histocompatibility complex (MHC) of immune functions and in the role that MHC... Read more about Chester Allen Alper
The Anthony Laboratory explores the role and regulation of IgG and IgE glycosylation in health and disease. These antibody classes are arguably the two most... Read more about Robert Anthony
Astrazeneca Professor of Respiratory and Inflammatory Diseases in the Department of Medicine
The central focus of the laboratory continues to be on the molecular and cellular biology of the mast cell, the pathways of arachidonic acid metabolism to... Read more about K. Frank Austen
Brigham and Women's Hospital
Department of Medicine; Division of Rheumatology, Immunology and Allergy
Building for Transformative Medicine
60 Fenwood Road, 5th Floor, Room 5002X
Boston, MA 02115
Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...
The overall goal of my lab is to apply principals of pathophysiology of allergic diseases in humans to questions at the bench, and in turn to bring fundamental... Read more about Joshua A. Boyce
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
The major scientific interest of the Butovsky lab is to understand the biology of resident microglia and peripheral innate immunity in brain homeostasis...
Our laboratory investigates the cell biological basis of inflammation and wound healing with special emphasis on leukocyte-endothelial interactions. The...
Work in my laboratory is directed at understanding the innate immune response to bacterial enteropathogens. Our focus is on Salmonella Typhimurium and... Read more about Bobby J. Cherayil
Department of Dermatology and MGH Cancer Center
Massachusetts General Hospital
Harvard Medical School
Cutaneous Biology Research Center
Building 149 13th Street, 3rd floor
Charlestown MA 02129
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Assistant Professor of Immunology and Infectious Diseases
Our body is colonized by a robust and diverse ecosystem - the commensal microbiome. When mucosal pathogens infect us, they first encounter our commensals... Read more about Smita Gopinath
Research in Dr. Hemler's laboratory is focused on novel mechanisms which affect tumor cell interactions with leukocytes, endothelial cells and fibroblasts...
The function of many proteins is regulated by post-translational modifications. One such modification is citrullination, which converts peptidylarginine...
Brigham and Women's Hospital
Department of Medicine; Division of Rheumatology, Immunology and Allergy
Building for Transformative Medicine (BTM)
60 Fenwood Road, Room 6002M
Boston, MA 02115
The major focus of my laboratory is to understand the role of the NF-κB family of transcription factors in regulating innate inflammatory responses. NF-κB...