Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...
The CBDM lab has varied interests, generally organized around the genomic control of immunological tolerance and autoimmune diseases in T lymphocytes. We...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
A major focus of our studies has been the elucidation of genetic pathways regulating tolerance and to identify human diseases resulting from defects along... Read more about Talal Chatila
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
The Smillie Lab uses systems approaches to understand the mechanisms of host-microbiome interactions. Our research interests are broad, spanning mucosal...
Research in my lab focuses on elucidating mechanisms regulating tissue homeostasis and inflammation. Mammalian tissues are ecological communities of...
