The Aster laboratory primarily studies Notch signaling in cancer. Ongoing projects seek to understand through use of ChIP-Seq and other comprehensive genome-... Read more about Jon Christopher Aster
Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...
B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
Morton Grove-Rasmussen Professor of Immunohematology
The CBDM lab has varied interests, generally organized around the genomic control of immunological tolerance and autoimmune diseases in T lymphocytes. We...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
The major scientific interest of the Butovsky lab is to understand the biology of resident microglia and peripheral innate immunity in brain homeostasis...
The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells...
A major focus of our studies has been the elucidation of genetic pathways regulating tolerance and to identify human diseases resulting from defects along... Read more about Talal Chatila
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
A major unresolved question in immunology is how specificity of gene activation is achieved after a particular cellular stress. The human tumor necrosis...
The Griffin Lab applies emerging functional genomic, sequencing, and immunologic tools to define fundamental mechanisms of immune regulation in tumors. We then... Read more about Gabriel Griffin
The Hemberg group carries out research in computational genomics, and our interests are in developing and applying algorithms for analyzing large high-...
The function of many proteins is regulated by post-translational modifications. One such modification is citrullination, which converts peptidylarginine...
Brigham and Women's Hospital
Department of Medicine; Division of Rheumatology, Immunology and Allergy
Building for Transformative Medicine (BTM)
60 Fenwood Road, Room 6002M
Boston, MA 02115
The major focus of my laboratory is to understand the role of the NF-κB family of transcription factors in regulating innate inflammatory responses. NF-κB...
We seek to develop and apply technologies (particularly revolving around high-dimensional tissue imaging) to address questions related to host-disease...
The Moody laboratory seeks to understand how human T cells control outcomes of infection and autoimmune disease. CD1 proteins are a family of evolutionarily... Read more about D. Branch Moody
Brigham and Women's Hospital
BTM Room 6002K
60 Fenwood Road
Boston, MA 02445