Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...

By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...

My laboratory focuses on the study of tissue resident T cells in humans. We isolate and study the T cells in human lung, cervix, decidua and...

The Early Life Development of the Immune System

The main focus of the Jain lab is to understand how immunity develops in early life. In utero,...

CD4+ T cell Tolerance

CD4+ T lymphocytes comprise a principal component of the adaptive immune system. These cells recognize processed antigens...

Inflammation and Memory as Drivers of Barrier Tissue Ecology

Our goal is to understand the principles of how inflammation drives memory...

The overall mission of this laboratory is to determine the mechanism of “crosstalk” between colonizing bacteria and the developing human intestine immune...

Inflammation is a protective response to noxious stimuli that originate from infections and injured tissues. The inflammatory process triggered in...