B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
The main focus of this laboratory is to elucidate the role of ATP and adenosine receptor signaling in immune cell activation. We have discovered that...
Over the last decade, critical discoveries in immunology and cancer biology have revealed how tumors are shaped by the immune system and how they evolve...
Center for Immunology and Inflammatory Diseases
Pulmonary and Critical Care Unit
Massachusetts General Hospital
Harvard Medical School
149 13th Street, Room 6-221
Charlestown, MA 02129
The main research focus of our laboratory is to establish the cellular, molecular, and genetic basis for the immunopathogenesis of susceptibility to develop... Read more about Edmond J. Yunis