Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...

The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells...

My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...

The main focus of this laboratory is to elucidate the role of ATP and adenosine receptor signaling in immune cell activation. We have discovered that...

The Kissler lab is studying mechanisms of immune regulation that fail in autoimmunity and in type 1 diabetes in particular.

The lab's research...

CD4+ T cell Tolerance

CD4+ T lymphocytes comprise a principal component of the adaptive immune system. These cells recognize processed antigens...

Inflammation is a protective response to noxious stimuli that originate from infections and injured tissues. The inflammatory process triggered in...