Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...

By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...

The major scientific interest of the Butovsky lab is to understand the biology of resident microglia and peripheral innate immunity in brain homeostasis...

My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...

Lipid signaling in immunity and inflammatory disease

My laboratory studies the biology of the bioactive lipid mediator- sphingosine 1-phosphate...

The function of many proteins is regulated by post-translational modifications. One such modification is citrullination, which converts peptidylarginine...

The major focus of my laboratory is to understand the role of the NF-κB family of transcription factors in regulating innate inflammatory responses. NF-κB...

Mucosal Immunobiology

The mucosal barriers of the body facilitate the arduous task of promoting symbiosis with the resident microbiota while...

The focus of the Kwon lab is the application of new technologies to the study of immune responses against HIV at mucosal surfaces.

Mucosal...

Inflammation and Memory as Drivers of Barrier Tissue Ecology

Our goal is to understand the principles of how inflammation drives memory...

Research in the Sage Lab focuses on understanding how the immune system regulates B cell responses and antibody production. Antibodies clear harmful...

The Smillie Lab uses systems approaches to understand the mechanisms of host-microbiome interactions. Our research interests are broad, spanning mucosal...

Immune cells play important roles in retinal vascular development/remodeling/repair and degeneration. Immune dysregulation during these processes in the...

Our group is devoted to investigating the way in which the functional, chemical and structural plasticity of neurons contributes both to the normal...

Research in my lab focuses on elucidating mechanisms regulating tissue homeostasis and inflammation. Mammalian tissues are ecological communities of...