B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
The main focus of this laboratory is to elucidate the role of ATP and adenosine receptor signaling in immune cell activation. We have discovered that...
