Our laboratory investigates the cell biological basis of inflammation and wound healing with special emphasis on leukocyte-endothelial interactions. The...

Our group studies how cell migration organizes the communication between the innate and the adaptive immune systems. Specifically, we are interested in...

CD4+ T cell Tolerance

CD4+ T lymphocytes comprise a principal component of the adaptive immune system. These cells recognize processed antigens...

We are motivated by the widespread understanding that a productive immune response always exerts some degree of collateral damage to healthy tissue....

The Sen laboratory investigates the regulation of T cell dysfunction and explores epigenetic approaches for T cell engineering. We have found that the...