The Aster laboratory primarily studies Notch signaling in cancer. Ongoing projects seek to understand through use of ChIP-Seq and other comprehensive genome-... Read more about Jon Christopher Aster
Our laboratory is broadly interested in targeting cancer innate immunity and in building novel technologies to model cancer immunotherapy response. We have... Read more about David Barbie
Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...
B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
Morton Grove-Rasmussen Professor of Immunohematology
The CBDM lab has varied interests, generally organized around the genomic control of immunological tolerance and autoimmune diseases in T lymphocytes. We...
Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...
Albert L. Sheffer Professor of Medicine in the Field of Allergic Disease
The overall goal of my lab is to apply principles of allergic and inflammatory disease pathophysiology in humans to questions at the bench, and in turn to... Read more about Joshua Boyce
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
The major scientific interest of the Butovsky lab is to understand the biology of resident microglia and peripheral innate immunity in brain homeostasis...
Our laboratory investigates the cell biological basis of inflammation and wound healing with special emphasis on leukocyte-endothelial interactions. The...
A major focus of our studies has been the elucidation of genetic pathways regulating tolerance and to identify human diseases resulting from defects along... Read more about Talal Chatila
Department of Dermatology and MGH Cancer Center
Massachusetts General Hospital
Harvard Medical School
Cutaneous Biology Research Center
Building 149 13th Street, 3rd floor
Charlestown MA 02129
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Our laboratory is a core laboratory in the MGH Brain Tumor Immunology and Immunotherapy Program. We are focused on understanding the immune response to...