Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
A major focus of our studies has been the elucidation of genetic pathways regulating tolerance and to identify human diseases resulting from defects along... Read more about Talal Chatila
We seek to develop and apply technologies (particularly revolving around high-dimensional tissue imaging) to address questions related to host-disease...
Research in the Sage Lab focuses on understanding how the immune system regulates B cell responses and antibody production. Antibodies clear harmful...