Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...

Our laboratory is a core laboratory in the MGH Brain Tumor Immunology and Immunotherapy Program. We are focused on understanding the immune response to...

The Hacohen lab consists of immunologists, geneticists, biochemists, technologists and computational biologists working together to develop new and...

Lipid signaling in immunity and inflammatory disease

My laboratory studies the biology of the bioactive lipid mediator- sphingosine 1-phosphate...

Mucosal Immunobiology

The mucosal barriers of the body facilitate the arduous task of promoting symbiosis with the resident microbiota while...

Inflammation and Memory as Drivers of Barrier Tissue Ecology

Our goal is to understand the principles of how inflammation drives memory...

The Smillie Lab uses systems approaches to understand the mechanisms of host-microbiome interactions. Our research interests are broad, spanning mucosal...

Research in my lab focuses on elucidating mechanisms regulating tissue homeostasis and inflammation. Mammalian tissues are ecological communities of...