Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-...
Morton Grove-Rasmussen Professor of Immunohematology
The CBDM lab has varied interests, generally organized around the genomic control of immunological tolerance and autoimmune diseases in T lymphocytes. We...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
A major focus of our studies has been the elucidation of genetic pathways regulating tolerance and to identify human diseases resulting from defects along... Read more about Talal Chatila
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Our laboratory is a core laboratory in the MGH Brain Tumor Immunology and Immunotherapy Program. We are focused on understanding the immune response to...
The Griffin Lab applies emerging functional genomic, sequencing, and immunologic tools to define fundamental mechanisms of immune regulation in tumors. We then... Read more about Gabriel Griffin
The Hacohen lab consists of immunologists, geneticists, biochemists, technologists, physicians and computational biologists working together to develop...
We seek to develop and apply technologies (particularly revolving around high-dimensional tissue imaging) to address questions related to host-disease...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
Over the last decade, critical discoveries in immunology and cancer biology have revealed how tumors are shaped by the immune system and how they evolve...
My laboratory studies pathomechanisms in wound healing and inflammation, utilizing human genetics, mouse genetics, and innovative OMICs technologies, as...
Research in the Sage Lab focuses on understanding how the immune system regulates B cell responses and antibody production. Antibodies clear harmful...
The Sen laboratory investigates the regulation of T cell dysfunction and explores epigenetic approaches for T cell engineering. We have found that the...