My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...

Lipid signaling in immunity and inflammatory disease

My laboratory studies the biology of the bioactive lipid mediator- sphingosine 1-phosphate...

Assembly and signal transduction of the T cell receptor for antigen. To examine the role of the CD3 genes in thymocyte development and in T cell function...

Research in my lab focuses on elucidating mechanisms regulating tissue homeostasis and inflammation. Mammalian tissues are ecological communities of...