B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells...
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Assistant Professor of Immunology and Infectious Diseases
Our body is colonized by a robust and diverse ecosystem - the commensal microbiome. When mucosal pathogens infect us, they first encounter our commensals... Read more about Smita Gopinath
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
The main focus of this laboratory is to elucidate the role of ATP and adenosine receptor signaling in immune cell activation. We have discovered that...
Over the last decade, critical discoveries in immunology and cancer biology have revealed how tumors are shaped by the immune system and how they evolve...
Our group studies how cell migration organizes the communication between the innate and the adaptive immune systems. Specifically, we are interested in...
Program Head, Graduate Program in Immunology Professor of Medicine he/him/his
Sialic acid O-acetylation, Siglecs and the regulation of hematopoiesis and immunity We are particularly interested in a novel set of pathways in which...
The study of histocompatibility in man and in other vertebrates led to the understanding of the mechanisms of immune recognition and to the discovery of...
The Tsokos laboratory studies immune cell signaling, metabolism and gene transcription in patients with systemic autoimmune diseases using state-of-the-art... Read more about George C. Tsokos
The main research focus of our laboratory is to establish the cellular, molecular, and genetic basis for the immunopathogenesis of susceptibility to develop... Read more about Edmond J. Yunis