The Aster laboratory primarily studies Notch signaling in cancer. Ongoing projects seek to understand through use of ChIP-Seq and other comprehensive genome-... Read more about Jon Christopher Aster
B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease....
The CBDM lab has varied interests, generally organized around the genomic control of immunological tolerance and autoimmune diseases in T lymphocytes. We...
Our group investigates mechanisms and signaling pathways involved in regulation of activating and inhibitory T cell responses. Mechanistic understanding...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation...
The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells...
Our laboratory investigates the cell biological basis of inflammation and wound healing with special emphasis on leukocyte-endothelial interactions. The...
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab...
Assistant Professor of Immunology and Infectious Diseases
Our body is colonized by a robust and diverse ecosystem - the commensal microbiome. When mucosal pathogens infect us, they first encounter our commensals... Read more about Smita Gopinath
Research in Dr. Hemler's laboratory is focused on novel mechanisms which affect tumor cell interactions with leukocytes, endothelial cells and fibroblasts...
The function of many proteins is regulated by post-translational modifications. One such modification is citrullination, which converts peptidylarginine...
Brigham and Women's Hospital
Department of Medicine; Division of Rheumatology, Immunology and Allergy
Building for Transformative Medicine (BTM)
60 Fenwood Road, Room 6002M
Boston, MA 02115
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
The main focus of this laboratory is to elucidate the role of ATP and adenosine receptor signaling in immune cell activation. We have discovered that...