Our laboratory is a core laboratory in the MGH Brain Tumor Immunology and Immunotherapy Program. We are focused on understanding the immune response to brain tumors in the context of the unique anatomic context of the central nervous system (CNS). ...
The research of my lab focuses on understanding how metabolites act as signaling molecules to regulate diverse biological processes. We apply state-of-the-art mass spectrometry, biochemical, and genetic approaches to identify mitochondrial metabolic...
Dr. Gravallese is the Theodore Bevier Bayles Professor of Medicine and Chief of the Division of Rheumatology, Inflammation and Immunity at Brigham and Women’s Hospital. The Gravallese laboratory is devoted to understanding the pathogenesis of systemic...
The Smillie Lab uses systems approaches to understand the mechanisms of host-microbiome interactions. Our research interests are broad, spanning mucosal immunology, microbiome evolution and ecology, and tissue biology, while relying on a combination of...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR technologies, physiological cell models such as organoids, and an interdisciplinary set of targeted...
My research focuses on understanding the balance between protective antitumor immunity and immunotherapy toxicities. In preclinical mouse models my lab develops novel immunotherapies designed to reduce systemic toxicities. This has involved a variety of...
Inflammation is a protective response to noxious stimuli that originate from infections and injured tissues. The inflammatory process triggered in response to microbial infections is instigated by pathogen-associated molecular patterns (PAMPs), while the...
Our group is devoted to investigating the way in which the functional, chemical and structural plasticity of neurons contributes both to the normal function and diseases of the nervous system. Our major efforts are devoted to the study of somatosensory...
Immunologists in the Winau Lab are most excited about the discovery of basic mechanisms that explain how the immune system functions. Over the years, we added to the passion for basic science a strong interest in identifying targets for possible...
Jatin M. Vyas received his PhD in Immunology working in the laboratory of Robert Rich at the Baylor College of Medicine. After completing his MD at Baylor, he performed his internship and medical residency at the Massachusetts General Hospital. He...
