Non Human Primates

The Penaloza-MacMaster Laboratory

Viral pandemics remain an enduring threat to humanity. The Penaloza-MacMaster Laboratory focuses on developing novel strategies to prevent and treat viral infections by integrating fundamental immunology with translational...

The major interests of the laboratory are the early events in human immunodeficiency virus (HIV-1) infection. Understanding and blocking these early events are critical to interrupting HIV-1 transmission and changing the course of the global AIDS pandemic...

Our laboratory focuses on the engineering of human monoclonal antibodies for their use in discovery research and as drugs for the treatment of human diseases. We are working in two broad disease areas: emerging infectious diseases and cancer. We have...

A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA damage, they induce the transcription of genes involved in cell cycle arrest and repair of the damage...

Our goal is to understand the role of neural-immune interactions in pain, host defense, and immunity. It is increasingly clear that microbes and immune cells release mediators that impact the health and function of the nervous system. Neurons also release...

Autoimmune Disease Deconstruction:

We have implemented a disease deconstruction pipeline using single cell and spatial technologies applied to inflamed tissues in humans to discover new cell types, cell states and pathways that mediate autoimmune disease...

 

Dr. Gaurav D. Gaiha, MD, DPhil, is an Assistant Professor of Medicine at Harvard Medical School and Attending Physician in the Division of Gastroenterology at Massachusetts General Hospital (MGH). Dr. Gaiha’s lab focuses on understanding the T cell...

We seek to develop and apply technologies (particularly revolving around high-dimensional tissue imaging) to address questions related to host-disease interactions in their native tissue context. By combining these methodologies with a systems approach...

I oversee the basic and translational research work of a team of lead investigators, postdoctoral fellows and other trainees who I mentor at the Vaccine and Immunotherapy Center (VIC) at Massachusetts General Hospital and Harvard Medical School. The goal...

Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine...