Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine...
Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-recognition receptors such as toll-like receptors and C-type lectin receptors sense danger in the...
Scientists currently in my laboratory:
Dr. Claire Guinier - Postdoctoral fellow
Dr. Bruno Gonzalez - Postdoctoral Fellow
Mr. Hyshem Lancia – PHD student
Ms. Natacha Carnel – PHD student
Our laboratory is studying the role of different pathways of antigen...
The laboratory studies mucosal immunity and focuses on several pathways that are especially relevant to the physiologic processes and diseases related to these compartments. As such, the laboratory has a particular interest in the manner in which...
By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation going, and can we do anything about it? The central theme of our laboratory is to understand the...
The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells that recognized the MHC class II and class I molecules and were equipped to mediate distinct...
The B cell receptor (BCR) is essential for survival of mature B cells and its specificity dictates the cells' fate from early development through final differentiation into an effector or memory cell. For example, immature B cells bearing a self-reactive...
My laboratory is interested in mechanisms and therapy of cancers. In the past years, I have been working on different types of hematologic and solid cancers. Most lymphomas, but also an increasing number of solid tumors, are characterized by defined...
Repair of Double stranded DNA breaks-pathway choices and more
Double stranded DNA breaks (DSBs) are critical for cell health as a single unrepaired DSB is sufficient for inducing apoptosis. Two major mechanistically distinct pathways, homologous...
My laboratory focuses on the study of tissue resident T cells in humans. We isolate and study the T cells in human lung, cervix, decidua and gastrointestinal tract but we have a particular interest in T cells at home to and reside within the skin.
Our...
Research Interests
Our lab’s major focus is on the mechanisms by which both immune and non-hematopoietic (tissue resident) cells maintain immune quiescence in both alloimmunity and autoimmunity. Our work has been instrumental in determining the cytokine...
