Cellular Immunology

Work in my laboratory is directed at understanding the innate immune response to bacterial enteropathogens. Our focus is on Salmonella Typhimurium and Salmonella Typhi, which cause acute gastroenteritis and typhoid fever, respectively. We use bacterial...

The Cantor lab studies the development and function of T-cell subsets. Early studies indicated that the thymus gave rise to two major lineages of T cells that recognized the MHC class II and class I molecules and were equipped to mediate distinct...

By the time we see patients in the clinic, pathology is usually established, and the flames of inflammation are already burning. What keeps inflammation going, and can we do anything about it? The central theme of our laboratory is to understand the...

Scientists currently in my laboratory:

Dr. Claire Guinier - Postdoctoral fellow
Dr. Bruno Gonzalez - Postdoctoral Fellow
Mr. Hyshem Lancia – PHD student
Ms. Natacha Carnel – PHD student

Our laboratory is studying the role of different pathways of antigen...

Innate immunity in the respiratory tract is exquisitely complex and tightly regulated, surveying 10,000 liters of air a day. While canonical pattern-recognition receptors such as toll-like receptors and C-type lectin receptors sense danger in the...

Dan Barouch received his Ph.D. in immunology from Oxford University and his M.D. from Harvard Medical School. He is currently the William Bosworth Castle Professor of Medicine at Harvard Medical School, Director of the Center for Virology and Vaccine...

Our laboratory is broadly interested in targeting cancer innate immunity and in building novel technologies to model cancer immunotherapy response. We have developed a microfluidic ex vivo system for culture of primary organotypic tumor spheroids that is...

The Aster laboratory primarily studies Notch signaling in cancer. Ongoing projects seek to understand through use of ChIP-Seq and other comprehensive genome-wide approaches how Notch regulates the genomes of leukemia cells; how Notch activity is...

The Anthony Laboratory explores the role and regulation of IgG and IgE glycosylation in health and disease. These antibody classes are arguably the two most clinically relevant antibodies. Our interests stem from well-known clinical paradoxes that are...

Research in the Anderson Laboratory focuses on understanding the pathways and mechanisms that regulate the T cell response in chronic disease, particularly in cancer. Specific areas of investigation are examination of the role of co-inhibitory/immune...