Myeloid Cells

The Hacohen lab consists of immunologists, geneticists, biochemists, technologists, physicians and computational biologists working together to develop new and unbiased technologies and strategies to understand basic immune processes and immune-mediated...

The Garrett Lab is interested in defining the dynamic interactions between the mucosal immune system and gut microbiota. Our experimental questions are grounded in understanding how interactions between intestinal microbial communities and the immune...

Hemostasis and Immunity Laboratory

Our laboratory aims to understand the role of the hemostatic factors (i.e., coagulation and fibrinolytic factors) in regulating inflammation at the mucosal barrier sites. The hemostatic and inflammatory systems have...

Our laboratory aims to understand the cellular and molecular interactions of the skeletal and immune systems in a relative recent branch of immunology termed osteoimmunology. Osteoimmunology studies the fundamental scientific principles that regulate the...

The major goal of the Guerriero lab is to accelerate breast cancer immunotherapy by harnessing tumor associated macrophages. To date, immunotherapy has largely focused on recruiting and activating anti-tumor T cells, which has shown tremendous responses...

Gut microbiota – the trillions of bacteria, fungi, viruses, and archaea that reside in our gut – contain a dynamic arsenal of products that can protect from or contribute to disease. Diet, medication, exercise, and disease impact the composition of the...

My laboratory studies pathomechanisms in wound healing and inflammation, utilizing human genetics, mouse genetics, and innovative OMICs technologies, as well as a broad array of functional assays. Our investigations are highly interdisciplinary and have...

Our laboratory is a core laboratory in the MGH Brain Tumor Immunology and Immunotherapy Program. We are focused on understanding the immune response to brain tumors in the context of the unique anatomic context of the central nervous system (CNS). ...

The research of my lab focuses on understanding how metabolites act as signaling molecules to regulate diverse biological processes. We apply state-of-the-art mass spectrometry, biochemical, and genetic approaches to identify mitochondrial metabolic...

Our group aims to understand the roles dendritic cells (DCs) play in the development and response to treatment of cancer.   DCs are a key bridge between innate and adaptive immunity, and are essential for cancer immunotherapy. These cells can also serve...