Ruth A. Franklin

Ruth A. Franklin

Assistant Professor of Stem Cell and Regenerative Biology
Ruth A. Franklin
Cells of the immune system defend us against a variety of insults, including infection by pathogens. However, it is now clear that immune cells also have important functions during development, tissue repair, and homeostasis. We use mouse models of infection, fibrosis, and cancer to investigate how immune cells sense and respond to both subtle changes in the tissue environment and extreme perturbations that drive inflammation. Our lab is particularly interested in the central role of macrophages and other innate immune cells in this process. We also aim to understand how cells of the immune system communicate with non-immune cell types within tissues, including fibroblasts and neurons, to elicit both local and systemic responses during homeostasis and disease.

Contact Information

Harvard Medical School
4BC Building, Room 818
4 Blackfan Circle
Boston, MA 02115
p: (617) 432-6152