Chemokines, resident memory effector and regulatory cells, and tissue immunity
Research in the Luster lab is varied and has historically focused on chemokines, immune cell trafficking, and resident memory effector and regulatory cells in regulating...
Research Interests
Our lab’s major focus is on the mechanisms by which both immune and non-hematopoietic (tissue resident) cells maintain immune quiescence in both alloimmunity and autoimmunity. Our work has been instrumental in determining the cytokine...
The Geha laboratory focuses on the molecular basis and mechanisms of (1) primary immune deficiency diseases and (2) atopic dermatitis.
Genetics and molecular basis of novel primary immunodeficiencies:
Primary immunodeficiencies (PID) are genetic...
Autoimmune Disease Deconstruction:
We have implemented a disease deconstruction pipeline using single cell and spatial technologies applied to inflamed tissues in humans to discover new cell types, cell states and pathways that mediate autoimmune disease...
The Dang lab studies the molecular and cellular interactions between fungi and their hosts. Mammalian barrier tissues (gut, skin, lungs) are constantly stimulated by microbes that play important roles in shaping host immunity and physiology. While fungi...
My laboratory focuses on the molecular mechanisms of innate immunity and inflammation leading to tissue destruction. More specifically, we are investigating the attack mechanisms instrumental in targeted tissues for autoimmune destruction. Conversely, we...
Immune cells play important roles in retinal vascular development/remodeling/repair and degeneration. Immune dysregulation during these processes in the eye leads to diseases such as retinopathy of prematurity and age-related macular degeneration. Our...
Mucosal Immunobiology
The mucosal barriers of the body facilitate the arduous task of promoting symbiosis with the resident microbiota while simultaneously preventing microbial invasion and pathogenic inflammation. We aim to uncover not only how tissue...
Innate and neuro-immune control of allergic immunity
The innate immune system plays a central role in adaptive immune initiation by sensing microbial invasion and environmental stress and using that information to promote specific adaptive immune...
